Latino people with CF suffer a greater burden from their disease with more severe pulmonary disease compared to non-Latino White people. Our focus is to understand the clinical, microbiology, environmental, and social factors that may be differentially contributing to more severe disease in Latino people. We are investigating pulmonary function using two approaches: using the CF Foundation Patient Registry and in our longitudinal cohort study.

The CF Foundation Patient Registry is the largest longitudinal database of Latino people with CF. We have investigated how pulmonary function is different in Latino people compared to non-Latino White people. We have found that Latino people FEV1 percent predicted was 5.7 percentage points lower than white patients. We also found the ethnic difference in pulmonary function was twice as wide in the West compared to the other regions of the United States (9.0% vs. 4.0-4.4%).

We are currently recruiting patients for a cohort longitudinal study of ethnic differences in factors that determine pulmonary function in CF. Do you wonder what affects lung disease in cystic fibrosis? We are investigating what clinical, microbiology, environmental, and social factors that may be differentially contributing to more severe disease in Latino patients.

We are recruiting Latino and non-Latino White children 0-21 years old for our study of lung function.

• Who? Latino or non-Latino White people with CF ages 0-21 years old

• What? Yearly visits over Zoom that include spirometry and questionnaires

• Visits conducted in English and/or Spanish

If you have CF and are interested in participating or learning more, click here!

Publications:
Pulmonary Function Disparities Exist and Persist in Hispanic Patients With Cystic Fibrosis: A Longitudinal Analysis

Regional variations in longitudinal pulmonary function: A comparison of Hispanic and non-Hispanic subjects with cystic fibrosis in the United States